BoneGuard Plus
BoneGuard Plus

BoneGuard Plus

Rs. 99.00
Cal-Mag-K2 + Omega-3 tablets for comprehensive skeletal & joint support
BoneGuard Plus delivers a balanced matrix of Calcium Citrate-Malate, Magnesium, high-potency Zinc, vitamins D₃ & K₂-7, plus EPA/DHA omega-3s—formulated for once-daily compliance.

Supplement Facts

Amount Per Serving
Calcium (as calcium citrate-malate) 250 mg 19 %
Magnesium (as magnesium oxide) 150 mg 36 %
Zinc (as zinc oxide) 50 mg 455 %
Vitamin D₃ (cholecalciferol) 1000 IU / 25 µg 125 %
Vitamin K₂-7 (menaquinone-7) 50 µg 42 %
EPA (eicosapentaenoic acid) 25 mg †
DHA (docosahexaenoic acid) 30 mg †
* Percent Daily Values are based on a 2,000 calorie diet.
  • Evidence-matched 1 000 IU vitamin D₃ shown to slow hip bone loss in post-menopausal women²
  • Bioavailable Calcium Citrate-Malate with synergistic trace minerals for mineralisation¹⁵
  • MK-7 (vit K₂-7) supports osteocalcin γ-carboxylation & bone quality⁴
  • Clinically studied magnesium for adolescent bone accrual³
  • Omega-3s provide anti-inflammatory precursors that may ease joint discomfort⁶
🎯 Indications
  • Helps maintain bone mineral density (BMD) & skeletal strength
  • Contributes to normal calcium absorption & utilisation
  • Supports collagen cross-linking & bone matrix integrity
  • Aids muscle function & reduces cramps via magnesium
  • May help modulate joint inflammation & comfort in physically active or osteoarthritic adults
⚙️ Mechanism of action
  • Calcium citrate-malate + Vitamin D₃ enhance intestinal Ca²⁺ absorption & suppress PTH-mediated resorption (human).
  • MK-7 prolongs activation of osteocalcin & Matrix-Gla Protein, directing Ca²⁺ to bone (human).
  • Magnesium acts as a co-factor for 1-α-hydroxylase & ATP-dependent bone turnover enzymes (human).
  • EPA/DHA generate resolvins & protectins that down-regulate NF-κB & COX-2 pathways (pre-clinical).
👥 Recommended patient profiles
  • Peri- & post-menopausal women with dietary Ca/Mg gaps
  • Men > 40 y with low sun exposure
  • Athletes with high musculoskeletal load
  • Individuals on long-term PPIs or low-fat diets limiting fat-soluble vitamin intake
💊 Dosage & administration

Take 2 tablets once daily with the main meal for optimal fat-soluble vitamin and omega-3 absorption.

⚠️ Safety & contraindications
  • Contains 50 mg zinc—exceeds adult UL (40 mg). Limit concurrent high-zinc products.
  • Vitamin K₂ may interfere with warfarin/anticoagulants; monitor INR.
  • Fish-derived omega-3s: avoid in severe fish allergy.
  • Pregnancy/lactation: consult healthcare professional.
  • Adverse effects rare; mild GI upset possible.
📦 Shelf life & stability
  • 24 months in HDPE bottle with 4 g silica desiccant
  • Store 15 – 25 °C, <60 % RH (ICH Zone IV B compliant)
  • Light-protected amber bottle + outer carton.
📚 References
  1. Lloyd T et al. Calcium supplementation and bone mineral density in adolescent girls. JAMA 1993;270:841-4. doi:10.1001/jama.270.7.841. (PubMed)
  2. Macdonald HM et al. Hip bone loss is attenuated with 1000 IU but not 400 IU vitamin D₃. J Bone Miner Res 2013;28:2202-13. doi:10.1002/jbmr.1959. (PubMed)
  3. Carpenter TO et al. Magnesium supplementation increases hip bone mineral content in healthy girls. J Clin Endocrinol Metab 2006;91:4866-72. doi:10.1210/jc.2006-1391. (PubMed)
  4. Knapen MHJ et al. Three-year low-dose MK-7 decreases bone loss in post-menopausal women. Osteoporos Int 2013;24:2499-507. doi:10.1007/s00198-013-2325-6. (PubMed)
  5. Strause L et al. Spinal bone loss in postmenopausal women supplemented with calcium and trace minerals. J Nutr 1994;124:1060-4. doi:10.1093/jn/124.7.1060. (PubMed)
  6. Deng W et al. Effect of omega-3 PUFA supplementation for osteoarthritis: meta-analysis of nine RCTs. J Orthop Surg Res 2023;18:381. doi:10.1186/s13018-023-03855-w. (PMC)